IMPROVED MANAGEMENT OF DRUGS, HORMONES AND PESTICIDES IN AFRICA : POLICY AND TRADE ISSUES


Xylose and shikimate transporters facilitates microbial consortium as a chassis for benzylisoquinoline alkaloid production

Abstract Plant-sourced aromatic amino acid (AAA) derivatives are a vast group of compounds with broad applications.Here, we present the development of a yeast consortium for efficient production of (S)-norcoclaurine, the key precursor for benzylisoquinoline alkaloid biosynthesis.A xylose transporter enables the concurrent mixed-sugar utilization in

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Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas

Infantile hemangiomas (IH) leave sequelae after involution.Topical application of timolol maleate (TM) is the mainstream treatment for superficial lesions but is limited by its low penetrable properties.We aimed to develop a superior skin permeation drug while maintaining the therapeutic properties of timolol.We predict that this drug will promote

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